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Facts of Life

Facts of Life:
Issue Briefings for Health Reporters
Vol. 9, No. 6
June 2004

Is There Light at the End of the Carpal Tunnel?

The Issue

The Facts

Curing Carpal Tunnel Syndrome

Expert Sources

References

The Issue:

Although often considered a white-collar malady, carpal tunnel syndrome and other repetitive stress disorders are injuries caused by frequent unvarying use of part of the musculoskeletal system. Repeated point-and-click motions may be the most publicized culprit, but repeated movements to assemble parts on a factory line and frequent use of motorized hand tools probably cause more cases of carpal tunnel syndrome. Repetitive stress injuries ranked among the top three causes of workplace injuries in 2002, costing more than $60 billion in lost wages, health care expenses, legal costs and worker’s compensation claims. [1].

Making the Diagnosis

The carpal tunnel syndrome diagnosis is very specific, involving inflammation and compression of the nerve and tendons that run through the carpal tunnel, a narrow passage linking the arm and hand that is created by the bones of the wrist and a tough ligament that binds the bones together. In common use, painful conditions like tendonitis and osteoarthritis get lumped under the complaint of “carpal tunnel,” making it difficult to determine what to treat.

Aggravating Conditions

Although research on carpal tunnel syndrome has centered on work habits and ergonomically unsound environments, recent studies suggest that factors like gender, obesity and overall stress levels could affect the risk of developing the syndrome and determine its severity.

The Facts:
  • Several studies suggest that women, people between the ages of 41 and 60 and those who are obese are more likely to have carpal tunnel syndrome. [8] A long-term study of industrial workers suggests a link between carpal tunnel syndrome and cigarette smoking. [9]

  • Rates of carpal tunnel syndrome increase with age for men, while the rates for women are highest between ages 45 and 54. [5]

  • Psychological distress may raise the risk of carpal tunnel syndrome. [10, 11]

  • A 2003 study found “no compelling scientific basis” behind genetic tests for carpal tunnel syndrome risk given to 20 railroad workers seeking injury compensation from their employer. [4]

  • Office machinery and hand tools caused more than 60 percent of carpal tunnel syndrome diagnoses in a Massachusetts workers’ comp case study. [2]

  • Medical data-entry workers who extended their wrists more than 20 degrees while typing were at greater risk of developing carpal tunnel syndrome than their co-workers, according to a Taiwanese study. [2]

  • A study of people who use computers for seven or more hours a day found no significantly higher incidence of carpal tunnel syndrome than in the general population, suggesting factors other than repetitive tasks may affect the disease’s development. [14]

  • New Hampshire employers who received regular inspections from local Occupational Safety and Health Administration officials saw a decline in the annual rate of carpal tunnel syndrome among their workers, from 38 cases in 10,000 to 3.8 cases in 10,000 over a five-year span. [7]

  • A carpal tunnel diagnosis involves more than pain: Only 1.4 percent of 5,658 Danish computer workers in a yearlong study had the full array of symptoms that are normally associated with carpal tunnel syndrome. [3]

  • Increased breathing rate and muscle tension across the upper body can accompany tasks like typing and using a computer mouse, possibly contributing to carpal tunnel syndrome even at ergonomic work stations. [13]

  • Surgical treatment relieves symptoms better than splint treatment in moderate to severe cases of carpal tunnel syndrome, according to a review of published studies. [6]

  • Highly repetitive tasks can damage bone in rats, suggesting that tasks like typing or hand tool use may cause similar damage in humans with carpal tunnel syndrome and other musculoskeletal disorders. [12]

Curing Carpal Tunnel Syndrome

Factory or office workers with a sore wrist, shooting pains up an arm and a crippled grip can testify to all the splints, pills and exercises they have tried in an attempt to find a cure for their condition. But as physicians readily admit, the exact diagnosis behind carpal tunnel syndrome and other repetitive stress disorders that affect the musculoskeletal system is still being debated. And it can be difficult to treat a disease unless its specific causes are well known.

“Because there are still so many questions about the underlying conditions, there’s uncertainty about the best type of treatment,” says Ann Barr, P.T., Ph.D., of Temple University. “Sufferers are often prescribed a package of treatments, including physical therapy, ergonomics and medication, and we’re not sure which treatment is actually working.”

Barr and her colleagues in the Temple School of Health Professions and School of Medicine were recently awarded a $1.7 million grant from NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases to find out whether work injuries caused by repetitive stress can be treated before they turn into a chronic disability.

Their five-year study will look at which treatments, from ergonomic work stations to doses of non-steroidal anti-inflammatory drugs like ibuprofen, work best for keeping conditions like carpal tunnel under control. Although such treatments are already commonly prescribed, Barr says it’s still not certain whether any of them “actually heal tissue.” The team hopes to identify the specific biological effects of each treatment type so that therapy can be better matched to a patient’s exact complaint.

Earlier research by Barr and colleagues sheds some light on the damage inflicted by repetitive motions — in rats. The researchers found that rats trained to reach for food pellets over and over again with the space of a few hours developed signs of inflammation and reabsorbed bone in their wrist and shoulders after 12 weeks. The low-stress repetitive reaching is similar to motions that occur while typing or continually placing parts on a factory assembly line, the scientists suggest, although they acknowledge only clinical studies can determine if those movements produce the same damage to human skeletal joints.

So far, researchers like Barr are concentrating on ways to keep repetitive stress injuries from getting worse. The biological studies could highlight certain behaviors that increase the risk of carpal tunnel syndrome and similar disorders and suggest changes in work patterns and environments. Barr says, however, that it is hard to get people to change their behaviors before they start feeling significant pain or discomfort, at which point the damage has already been done.


Expert Sources:

Ann E. Barr, P.T., Ph.D.
Temple College of Health Professions
(215) 707-5964
aebarr@temple.edu

Kurt T. Hegmann, M.D., M.P.H.
University of Utah School of Medicine
(801) 587-3333
khegmann@dfpm.utah.edu

Alan Hedge, Ph.D., C.P.E.
Cornell University
(607) 255-1957
ah29@cornell.edu

Marie Haring-Sweeney
National Institute for Occupational Safety and Health
(513) 533-8339
marie.sweeney@cdc.hhs.gov

References

1. News release, August 31, 2002. American Academy of Orthopaedic Surgeons: “Musculoskeletal Disorders Are the No. 1 Workplace Injury in America.” Last accessed at http://www.newswise.com/articles/view/31441/ on May 10, 2004.

2. Wellman, H. et al. (2004) Work-related carpal tunnel syndrome (WR-CTS) in Massachusetts, 1992-1997: source of WR-CTS, outcomes, and employer intervention practices. American Journal of Industrial Medicine, 45, 139-152.

3. Liu, C.W. et al. (2003) Relationship between carpal tunnel syndrome and wrist angle in computer workers. Kaohsiung Journal of Medical Science, 1112, 617-623.

4. Andersen, J.H. et al. (2003) Computer use and carpal tunnel syndrome: a 1-year follow-up study. Journal of the American Medical Association, 289, 2963-2969.

5. Schulte, P.A. and G. Lomax (2003) Assessment of the scientific basis for genetic testing of railroad workers with carpal tunnel syndrome. Journal of Occupational and Environmental Medicine, 45, 592-600.

5. Nakasato, Y.R. (2003) Carpal tunnel syndrome in the elderly. Journal of the Oklahoma State Medical Association, 96, 113-115.

6. Verdugo, R.J. et al. (2003) Surgical versus non-surgical treatment for carpal tunnel syndrome. Cochrane Database of Systematic Reviews, 3, CD001552.

7. May, D.C. (2002) Results of an OSHA ergonomic intervention program in New Hampshire. Applied Occupational and Environmental Hygiene, 11, 768-773.

8. Becker, J. et al. (2002) An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome. Clinical Neurophysiology, 1113, 1429-1434.

9. Nathan, P.A. et al. (200222) Predictors of carpal tunnel syndrome: an 11-year study of industrial workers. Journal of Hand Surgery, 24, 644-651.

10. Roquelaure Y. et al. (2001) Prevalence, incidence and risk factors of carpal tunnel syndrome in a large footwear factory. International Journal of Occupational Medicine and Environmental Health, 14, 357-367.

11. Lundberg, U. (2002) Psychophysiology of work: stress, gender, endocrine response, and work-related upper extremity disorders. American Journal of Industrial Medicine, 41, 383-392.

12. Barr, A. E. et al. (2003) Repetitive, negligible force reaching in rats induces pathological overloading of upper extremity bones. Journal of Bone and Mineral Research, 18, 2023-2032.

13. Peper, E. et al. (2003) The integration of electromyography (SEMG) at the workstation: Assessment, treatment and prevention of repetitive strain injury (RSI). Applied Psychophysiology and Biofeedback, 28, 167-182.

14. Stevens, J.C. et al. (2001) The frequency of carpal tunnel syndrome in computer users at a medical facility. Neurology, 56, 1568-1570.

The Center for the Advancement of Health is an independent nonprofit organization that promotes greater recognition of how psychological, social, behavioral, economic and environmental factors influence health and illness. The Center advocates the highest quality research and communicates it to the medical community and the public. The fundamental aim of the Center is to translate into policy and practice the growing body of evidence that can lead to the improvement and maintenance of the health of individuals and the public. The Center was founded by the John D. and Catherine T. MacArthur Foundation and the Nathan Cummings Foundation, which continue to provide core funding. Funding for this series was provided by the Robert Wood Johnson Foundation.

For Information Contact:
Kristina Campbell
Editor, Health Behavior News Service
Center for the Advancement of Health
2000 Florida Ave., NW, Suite 210
Washington, DC 20009
p. 202.387.2829 / f. 202.387-2857
press@cfah.org
http://www.cfah.org

© Copyright 2004, Center for the Advancement of Health

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